Susceptibility of bovine macrophages to infectious bovine rhinotracheitis virus infection

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Susceptibility of bovine macrophages to infectious bovine rhinotracheitis virus infection.

Infectious bovine rhinotracheitis virus replicated in cultured bovine alveolar macrophages (AM). However, yields of infectious virus were low, with maximum titers approximately 100 times that of the residual inoculum. Immunofluorescence and electron microscopic studies indicated that the majority of macrophages produced viral antigen, but after infection at a multiplicity of 0.1, only 4.1% of A...

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Infectious bovine rhinotracheitis.

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Sensitivity of infectious bovine rhinotracheitis virus to ether.

The sensitivity of 12 field isolates of infectious boviine rhinotracheitis (IBR) virus and four commercial modified-live infectious bovine rhinotracheitis virus vaccine strains was determined after exposure to 20% ethyl ether (anesthetic) for 16 h at 4 c. The infectivity of five field strains was reduced by varying degrees, whereas seven were found to be resistant. Three vaccine strains were mo...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1982

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.35.3.1048-1057.1982